Individuals with TRD (\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$n=2199$$\end{document}n=2199) observationally had higher CRP and BMI compared with individuals with MDD alone and healthy controls. Here, CRP is linked to major depressive disorder.