Anti-angiogenesis, initiation of apoptosis, and decrease of cellular proliferation were found to have antitumor effects on gastric adenocarcinoma cells ex-vivo, along with modulating the expression levels of the cancer-related genes Akt, PCNA, Bax, P53, and Bcl2 [228] (Fig. 3). The gene discussed is AKT1; the disease is cancer.