Moreover, RCN3, along with α-SMA and collagen-I, was upregulated in disease lung fibroblasts derived from an IPF patient (DHLF-IPF, from merchandise Lonza) versus normal human lung fibroblast (NHLF, from merchandise Lonza), which was consistent with observations in fibroblasts isolated from patient lungs (Fig. 1B). The gene discussed is RCN3; the disease is glycogen storage disease VI.