We found that FERMT3, HSP90B1, GNAI2 and GRK2 were similarly expressed in CD4+ T cell clusters from participants with MS and controls, while the expression levels of ITGA4, CXCR3, S1PR1 and ETS1 were significantly higher in some of the T cell clusters from participants with MS (Fig. 7g). Here, ITGA4 is linked to myeloid sarcoma.