HSP90B1, GNAI2 and S1PR1 expression levels in CD4+ T cell clusters from participants with MS were significantly correlated with their likelihood of migration into the CNS, while the expression level of ETS1, which limits CNS migration of T cells in rats, showed a trend toward a negative correlation with migration propensity (Fig. 7f). This evidence concerns the gene GNAI2 and myeloid sarcoma.