The presence of hypoglycemia and hyperlactatemia after feeding raised the suspicion of glycogen storage disease type 0 (GSD-0), but sequencing of the glycogen synthase 2 (GYS2) gene, responsible for GSD-0, identified only one heterozygous, unclassified missense variant (c.1636A>G) predicted to be benign. Here, GYS2 is linked to Hypoglycemia.