For example, BMI was independently associated with GH AUC during hypoglycemia (R2 = 0.167, model P = .010, std β = −.308, P = .028, fasting glucose also included in model) and glucagon ΔAUC (R2 = 0.652, model P < .001, std β = .255, P = .022, HbA1c and M-value also included in model) during hyperglycemia. This evidence concerns the gene GCG and Hyperglycemia.