Additionally, in a subset of donors where the data were available, the residual CD103+ Vγ2/3/4+ T cells in UCI and CDI showed atypically high frequencies of CD5+ cells (Fig. 4I) which in the healthy colon is a phenotype more often associated with CD103negVγ2/3/4+ cells as considered above (see Fig. 1F). This evidence concerns the gene ITGAE and clostridium difficile infection.