It showed that THBS1-IT1 was positively correlated with immune scores (r > 0.5, P < 0.001) in esophageal carcinoma (ESCA), KICH and pheochromocytoma and paraganglioma (PCPG) (Supplementary Figure 14). Here, THBS1 is linked to hereditary pheochromocytoma-paraganglioma.