LEF1 and neoplasm: Firstly, we compared the expression levels of 8 CarLncs between tumor and adjacent tissues and found that THBS1-IT1, LINC01871, LEF1-AS1-201, CCL3-AS1-202, GRAPLDR and WDR11-DT-201 were significantly differentially expressed (Supplementary Figure 3, P<0.05), suggesting these 6 lncRNAs are related with both aging and KIRC.