KM-OS analysis showed that among the patients of ACC, BLCA, GBM, HNSC, KIRC, LGG, MESO, PAAD, STAD and thyroid carcinoma (THCA), those who expressed higher levels of THBS1-IT1 had shorter survival time; in addiction, it also demonstrated a negative correlation was observed between THBS1-IT1 expression level and outcome in ACC, BLCA, GBM, HNSC, KIRC, LGG and PAAD (Supplementary Figure 7 log-rank test P < 0.05). This evidence concerns the gene THBS1 and glioblastoma.