CASR and lung carcinoma: Figure 1A shows that FIH expression is abundant in both the cytoplasm and nucleus of lung cancer cells. We found that FIH is present in all lung tumor samples tested, with varying degrees of expression (Figure 1A and Supplemental Figure 3). In addition, FIH is mainly found in the cytoplasm of the lung cancer cells LLC, NCI-H1581, A549, and NCI-H460 (Supplemental Figure 4).