IL6 and atrial fibrillation: In a previous study on atrial fibrillation, hypertrophic adipocytes and activated macrophages secreted tumor necrosis factor‐α and interleukin‐6 (IL‐6) to activate NOD‐like receptor family protein‐3 (NLRP3) inflammatory pathway and promote atrial fibrosis and electrical remodeling.21, 22, 23