Among DLBCL NOS (n = 296), the frequency of SNV was PIM1 (n = 101, 34.1%), TP53 (n = 79, 26.7%), CD79B (n = 72, 24.3%), BTG1 (n = 71, 24.0%), and HIST1H1E (n = 70, 23.6%). This evidence concerns the gene H1-4 and diffuse large B-cell lymphoma.