In order to promote pro‐carcinogenic pathways, NF‐κB and STAT3 are activated,56, 57, 61 and mitogens such as amphiregulin, epiregulin, and hepatocyte growth factor (HGF) produced by TLR‐expressing fibroblast cells have cancer‐causing effects.57, 61, 62, 63. The gene discussed is HGF; the disease is cancer.