To ascertain the mechanism by which the PTTG3P/ILF3 complex drives the malignant progression of NSCLC and to determine the changes to downstream coding-gene expression levels of PTTG3P, we evaluated the global mRNA effects of PTTG3P knockdown by using RNA transcriptome sequencing (Fig. 5A, left panel). Here, ILF3 is linked to non-small cell lung carcinoma.