The top 20 upregulated or downregulated lncRNAs in NSCLC are shown in Fig. 1A. Since lncRNAs with high expression are more feasible for use as markers for early diagnosis or response to treatment of NSCLC, we chose lncRNA PTTG3P, which is a lncRNA highly expressed in NSCLC. This evidence concerns the gene PTTG3P and non-small cell lung carcinoma.