Analysis of cell viability showed that p53-deficient cells were more sensitive to the Terbinafine than p53-proficient cells (Figure 3F-H), which is consistent with the bioinformatics analysis of DepMap data showing that p53-mutant CRC cell lines display a higher dependency on SQLE than p53 wt cells (Figure 1D). The gene discussed is TP53; the disease is colorectal carcinoma.