MT1E and hydrops fetalis: Interestingly, genes associated with metabolisms of zinc and copper ions (eg. genes named MT1E, MT2A, MT1X, MT1G) were significantly increased their expression levels in almost all the major cell types (including immune cells of T cells, monocytes, macrophages and cDCs, and non-immune cells of lymphatic EC and SMCs), suggesting that the metabolism of zinc and copper ion was disturbed in EAT from adult patients with HF.