KEGG analysis revealed that the most significantly enriched pathway was the PI3K‐AKT signaling pathway (Figure 3B), which has been reported to regulate LCN2 expression.[13] We also validated a potential correlation of PGAM1 with LCN2, AKT, and ferroptosis markers based on five HCC datasets (Figure S8, Supporting Information). The gene discussed is AKT1; the disease is hepatocellular carcinoma.