CD274 and hepatocellular carcinoma: validated that mitochondrial translocator protein (TSPO) promotes HCC progression by inhibiting ferroptosis and promotes HCC immune escape by upregulating PD‐L1 expression through Nrf2‐mediated transcription.[28] Another study reported that targeted xCT‐mediated ferroptosis and pro‐tumoral polarization of macrophages is effective against HCC and enhances the efficacy of the anti‐PD‐1/L1 Response.[29] Moreover, we considered the potential toxicity or other side effects of KH3.