According to several studies, USP18 belongs to the USP subfamily of deubiquitinating enzymes (DUBs) that stabilize PD‐L1 expression levels and then influence the immune response.[23, 24] This led us to assess the correlation coefficients between PD‐L1 and 65 DUBs; we found that USP18 or lncRNA BCCE4 was significantly correlated with PD‐L1 in bladder cancer tissues (Figure 4H; and Figure S28A,B, Supporting Information). The gene discussed is CD274; the disease is urinary bladder cancer.