Serum 25(OH)D levels (OR = 0.987, 95% CI = 0.998–0.977, P = 0.022) and IL-5 (OR = 1.207, 95%CI = 1.327–1.098, P = 0.000) were strongly associated with COVID-19 severity (Table 3). The gene discussed is IL5; the disease is COVID-19.