IL10 and myeloid sarcoma: For example, IL-10 serum levels trended higher in a meta-analysis of MS versus controls [50] and elevated IL-10 levels (1) are observed in chronic active lesions in post-mortem MS brain [51], (2) are present in cerebrospinal fluid of MS patients [50, 52] and (3) longitudinally predict 5-year worsening of EDSS in progressive patients [53].