LATS2 and neoplasm: However, other reports have pointed out that miR-200b-3p can exert oncogenic functions as showing the promotion of tumor progression by downregulating some tumor suppressor genes, including cassette subfamily A member 1 (ABAC1), large tumor suppressor kinase 2 (LATS2) and transcriptional intermediary factor 1 γ (TIF1γ) [58–60].