6) LPS did not have significant effect on IL gene expression in this study, similar to those showing that LPS does not increase IL6, IL8 and IL15 expression in two human colon cancer cell lines [3], but differ from two reports about LPS effect on IL6 and IL8 mRNA levels in HT-29 cells [50, 51]. Here, IL6 is linked to malignant colon neoplasm.