Among the number of 10 TWAS-significant genes, six were previously reported as susceptible to GSD and/or CAD (GWAS Catalog accessed by December 20, 2022), including SPPL3, C12orf43, DAGLB, and UNC119B associated with lipid metabolism (closely relevant to GSD and CAD), SNRPD2 associated with CAD, and RAC1 associated with CAD and lipid metabolism. The gene discussed is SNRPD2; the disease is coronary artery disorder.