Causes of PVCT were: [1] 4 cases of thrombophilia such as dysfunction of antithrombin III or proteins C; [2] 4 cases secondary to abdominal surgeries, which were further stratified as 2 orthotopic liver transplantation, 1 ex vivo liver resection, 1 bile duct jejunum Roux-en-Y anastomosis; [3] 4 cases secondary to abdominal infection or traumatic intestinal obstruction, including 1 pancreatitis, 1 portal phlebitis secondary to appendicitis, 1 intestinal obstruction, 1 liver trauma; and [4] 8 cases with unknown causes. This evidence concerns the gene SERPINC1 and appendicitis.