Both rs2736191 and another NCR3 variant rs11575837:C>T (located in the non-coding region of exon 1) have been shown to be inversely associated with risk of primary Sjögren’s syndrome (pSS), and the minor T allele of rs11575837 is associated with reduced NCR3 gene transcription [30, 31]. Here, NCR3 is linked to Sjogren syndrome.