To conclude, GNG7-related immunomodulators were identified through the TISIDB online website, and a prognostic prediction model for CCRCC patients was constructed based on key immune prognostic genes, and then the expression of GNG7 in CCRCC was validated using the GEO external validation set and immunohistochemical experiments. The gene discussed is GNG7; the disease is nonpapillary renal cell carcinoma.