GNG7 and autoimmune thyroid disease: As shown by the KEGG volcano map, T cell receptor signaling pathway, Intestinal immune network for IgA production, Natural killer cell mediated cytotoxicity, Autoimmune thyroid disease and other pathways were related to the immune status mediated by GNG7-related immune modulators (Fig. 8B), which again verified that GNG7 might participate in and mediate the immune events of CCRCC.