Among the retained target genes of hsa-mir-376a-1_49g, hsa-mir-376c_48g and hsa-mir-29c_59u, BCAT1, MTHFD2 and RASSF8 were further analyzed after examining their functional relevance in ccRCC by reading their literature, respectively. This evidence concerns the gene BCAT1 and nonpapillary renal cell carcinoma.