Six of these proteins were upregulated in DLB (DDC, GH, IDUA, PRCP, KYNU, and ENTPD5) and eight proteins were downregulated (CRH, FCER2, MMP1, COL4A1, WIF1, PAM, VEGFA and CTSC, Fig. 1b, Supplementary Dataset 1). The gene discussed is PAM; the disease is Lewy body dementia.