CRP and obesity due to melanocortin 4 receptor deficiency: When comparing the high-fiber Dietary Approach to Stop Hypertension (DASH) and fiber-supplemented (psyllium) diet in hypertensive subjects with obesity and normotensive lean subjects, both diets showed significant reductions in CRP, with the fiber-supplemented diet having a greater effect on normotensive lean subjects but not on hypertensive subjects with obesity [49].