For example, the post-menopausal African-American female with metabolic syndrome may have either low or adequate status for any of the micronutrients, she may or may not have high Lp(a), low muscle mass, low bone mineral density, sensitivity to gluten, high C reactive protein, etc. The more narrowly we define the population group of interest the more we realize that there are as many population groups as there are individuals. The gene discussed is CRP; the disease is metabolic syndrome.