Furthermore, molecular signaling markers associated with depressive and anxiety-like behaviours such as the protein kinase B (Akt), glycogen-synthase-kinase-3 (GSK-3), mammalian target of rapamycin (mTOR), brain-derived neurotrophic factor (BDNF), dopamine (DA) D1, and D2 receptor subtypes are dysregulated following stress exposure [35-40]. The gene discussed is AKT1; the disease is Anxiety.