CXCR3 and Sepsis: As a CXC chemokine, IP-10 can specifically bind to chemokine (C-X-C motif) receptor 3 (CXCR3) to promote T lymphocyte migration and neutrophil infiltration [18–20], and the IP-10–CXCR3 axis has been suggested to be critical for exacerbating the pathological process of sepsis [21,22].