METTL14 (Li et al., 2021a), YTHDC1, and WTAP (Cui et al., 2022) may be protective factors for bladder cancer, the higher expressions were related to the longer overall survival of patients, while IGF2BP1-3 (Xie et al., 2021), YTHDF1 (Zhu et al., 2023), LRPPRC (Cui et al., 2022), ALKBH5, and FTO (Deng et al., 2022) were risk factors for bladder cancer. This evidence concerns the gene ALKBH5 and urinary bladder cancer.