METTL14 (Li et al., 2021a), YTHDC1, and WTAP (Cui et al., 2022) may be protective factors for bladder cancer, the higher expressions were related to the longer overall survival of patients, while IGF2BP1-3 (Xie et al., 2021), YTHDF1 (Zhu et al., 2023), LRPPRC (Cui et al., 2022), ALKBH5, and FTO (Deng et al., 2022) were risk factors for bladder cancer. The gene discussed is IGF2BP1; the disease is urinary bladder cancer.