Through research and analyses, it was found that METTL14 level was negatively linked with tumor size, metastasis stage, pathological grade, and TNM stage (Zhang et al., 2021a; Liu et al., 2022d), and METTL14 could increase lymph node metastasis, liver metastasis and mortality rate of BC mouse model (Liu et al., 2022a). Here, METTL14 is linked to breast cancer.