While GSEA analysis indicated that several tumor hallmarks were enriched in the high EXOSC10 expression group, such as E2F target, MTORC1 signaling pathway, PI3K-AKT-MTOR signaling pathway, p53 signaling pathway, TGF beta signaling pathway, and WNT beta-catenin signaling pathway (Fig. 3B). This evidence concerns the gene AKT1 and neoplasm.