Further ROC curve analysis showed that a total of 11 key genes (ATIC, BCL2, EEF2, EIF2AK3, HSPA8, IKBKB, NLRC4, PARP1, PRKCQ, SH3GLB1, and WIPI1) had AUCs greater than 0.90 both in GSE65682 and GSE134347, and these genes were considered to have diagnostic efficacy for sepsis (Figures 7A, B). The gene discussed is WIPI1; the disease is Sepsis.