Apoptosis (BCL6, CTSS, ACTB, TUBA1A, BCL2A1), protein processing in endoplasmic reticulum (HSPA1B, XBP1), and lysosomes (LAPTM5, PSAP, GNS, LITAF) pathways regulated by these genes are responses to infection and injury (Figure 4B-ii). The gene discussed is BCL2A1; the disease is infection.