To confirm the clinical significance of LINC02774 and examine whether the downstream targets of LINC02774 exhibit consistent changes in clinical glioma specimens, we analyzed the expression levels of LINC02774, PHD3, RP58, HIF‐1α, VEGF, and GLUT1 in different grades of glioma tissues. The gene discussed is ZBTB18; the disease is central nervous system cancer.