IGF1 and lung cancer: We considered two proteins, Cyclin-Dependent kinase 2 (CDK2) with PDBID: 1AQ1 and Insulin-like Growth Factor 1 Receptor (IGF1) withPDBID: 1K3A, which show primary indicators and play a role in the pathogenesis of lung cancer [25,26].Protein crystal structure (3D structure) was taken from the RCSB database and importedinto the Schrodinger Maestro workspace for preparation and optimisation.In 1AQ1, there is chain A with solvent and ligands; however,we kept chain A as it is and removed solvent from the protein.