Besides, taken together with the above-mentioned elevation of anti-MDA5 antibodies in COVID-19, the finding that hyperferritinemia paralleled with high levels of inflammatory mediators in the peripheral blood in patients with COVID-19 seems to reinforce the similarity between the two diseases and points to the possible involvement of viral infection in the pathogenesis of MDA5+ DM. The gene discussed is IFIH1; the disease is isolated hyperferritinemia.