However, alkylglyceronephosphate synthase (AGPS) is highly expressed in aggressive breast (231MFP), melanoma (C8161) and prostate cancer (PC3) cells compared with less aggressive cancer cells (MCF7, MUM2C, and LNCaP, respectively) suggesting that AGPS is an important player in the aggressiveness of cancers [17]. The gene discussed is AGPS; the disease is Familial prostate cancer.