The premise that individuals living further from the tropics absorb lower UVB light and thus have greater vitamin D insufficiency and a greater menace of MS is a considerable clinical link between MS and vitamin D. The discrepancy between the benefits of ultraviolet irradiation and possessions of vitamin D on MS jeopardy is just adequately controlled for an observational study since ultraviolet exposure can also limit the formation of MOG EAE. The gene discussed is MOG; the disease is myeloid sarcoma.