TLR4 and polycystic ovary syndrome: Therefore, we speculated that MOL upregulated the expression of Blautia, Oscillospira, Adlercreutzia, and Parabacteroides and downregulated the expression of Fusobacteria, Fusobacterium, and Prevotella, which in turn downregulated the expression of TLR4 for reducing inflammation to improve the PCOS.