eGFR estimated from creatinine only and from cystatin C only: 1) produce nearly indistinguishable Kaplan-Meier estimates of the time to achieve an eGFR<20 mL/min/1.73m2 [234] and 2) produce very similar hazard ratios for KFRT [42], CKD progression [235] and all-cause mortality [235]. Here, CST3 is linked to chronic kidney disease.