Wang Jing et al. (Feng et al., 2014b) on studying the HPS effect on the expression of TIR-Domain-Containing Adapter-Inducing Interferon-β (TRIF) and tumor necrosis factor receptor-related factor 6 (TRAF6), a key molecule in the toll-like receptor 4 (Toll-4) signal transduction pathway in uveitis (EIU) model rats, found that intraperitoneal injection of 400 mg/kg HPS in rats lowers the mRNA expression of TRAF6 and nuclear factor-κB (NF-κB). The gene discussed is TLR4; the disease is Hermansky-Pudlak syndrome.