In this study, we observed that the levels of CD4+FOXP3+ T-regs in preeclampsia were significantly reduced when compared to both normal pregnant women (p < 0.001) and normal non-pregnant women (p < 0.001).Toldi G et al. investigated the proportion of T-regs and their cellular network in preeclamptic women, and they have seen that the proportion of T-regs and that of naive CD4+CD45RA+ cells were lower in preeclamptic than in control women. Here, CD4 is linked to preeclampsia.