Despite the p-values for AUCs of some genes such as AP3B2, BLOC1S1, NUDT13, PTCH1, and ZNF609 being statistically significant in all three breast cancer subtypes, their significance in HER2+ cancers and TNBC were much lower compared to that in ER+/HER2- breast cancer patients. This evidence concerns the gene ESR1 and breast carcinoma.