With upregulation in its expression in PBMCs from psoriasis patients, miRNA-148a has been shown to facilitate differentiation of inflammatory monocyte-derived dendritic cells via PU.1–miR-148a–MAFB axis, albeit with no report in the context of psoriatic lesions, Keratinocytes, T cells, or peripheral circulation (84). Here, SPI1 is linked to psoriasis.