Considering that there were few studies on Collagen family genes in gastric cancer, we performed the bioinformatics analysis of COL1A1, COL2A1, COL3A1, COL4A1, COL5A1, COL6A1, COL7A1, COL8A1, COL9A1, COL10A1, COL11A1 and COL12A1. The gene discussed is COL10A1; the disease is gastric cancer.