To explain the role of these TFs, ETV4 is involved in proliferation and induction of differentiation-associated genes65 and promotes breast cancer cells66, SOX10 has a positive regulation on epithelial cell proliferation67, GTF3C1 has been introduced as an immune-related marker for breast cancer68 by modulating cell proliferation, invasion, adhesion, angiogenesis and survival69, MAFB regulates dendritic cell maturation, the master regulator of the immune response70, is an inducer of monocytic differentiation71, and macrophage development72. This evidence concerns the gene MAFB and breast carcinoma.