Garcia-Bermudez et al. studied the sensitivity of tumor cells to mitochondrial ETC inhibitors and found that tumor cells insensitive to ETC inhibition maintain intracellular Asp concentrations through the Asp/glutamate transporter SLC1A3, which gives tumor cells a survival advantage.92 In another study on tumor metabolism, Sullivan et al. found that Asp synthesis was a limiting factor for bladder cancer growth when oxygen was lacking in the environment. Here, SLC1A3 is linked to neoplasm.