CCL2 and Anxiety: To further explore the role of CCL2 in the anxiety of high myopes, we analyzed human blood samples with a suspension cytokine array and identified significantly higher levels of CCL2 in the blood of highly myopic patients (30.04 ± 14.19 pg/mL vs 24.64 ± 14.63 pg/mL in the control, P = 0.0073; Fig. 1c).