PTPRC and myopia: We found that the chimeric mice with high myopia presented significantly increased ratio of GFP+/CD45+ cells in both the uvea (0.44 ± 0.19% vs 0.07 ± 0.04% in the control, P = 0.0012) and the brain (0.16 ± 0.04% vs 0.04 ± 0.02% in the control, P < 0.0001) (Fig. 3e).