Both the total and psychic anxiety scores correlated positively with the CCL2 and monocyte levels in the blood of highly myopic patients (CCL2: r = 0.350 and 0.349, respectively, both P = 0.0003; Fig. 1e; monocytes: r = 0.814 and 0.695, respectively, both P < 0.05; CD14+/CD68+ monocytes: r = 0.815 and 0.790, respectively, both P < 0.01; Fig. 1f). This evidence concerns the gene CCL2 and Anxiety.