AXIN1 and hepatocellular carcinoma: Excessive Wnt signaling activation has been reported in several subgroups of HCC, that is, the “Wnt‐TGFβ subclass,” the “progenitor subclass” with mutations in AXIN1, and the relatively more heterogeneous “non‐proliferation class” with mutations in the β‐catenin gene CTNNB1 [7, 8].